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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADCY1 All Species: 21.52
Human Site: Y1033 Identified Species: 52.59
UniProt: Q08828 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08828 NP_066939.1 1119 123440 Y1033 R L L R R C P Y H F V C R G K
Chimpanzee Pan troglodytes XP_519081 1119 122966 Y1033 R L L R R C P Y H F V C R G K
Rhesus Macaque Macaca mulatta XP_001086268 1119 123304 Y1033 R L L R R C P Y H F V C R G K
Dog Lupus familis XP_849081 1161 127825 Y1063 R L L R R G T Y R F V C R G K
Cat Felis silvestris
Mouse Mus musculus O88444 1118 123354 Y1032 R L L K R C S Y Q F V C R G K
Rat Rattus norvegicus Q03343 1166 130488 I1083 F N N F Q M K I G L N M G P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9DGG6 1334 149273 Y1203 R I L S K M G Y D F D Y R G T
Frog Xenopus laevis P98999 1305 145393 Y1212 R V L V K M G Y D F D Y R G T
Zebra Danio Brachydanio rerio NP_001161821 1114 124608 D1026 R L L S G Y Y D F N C R G Q V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P32870 2248 248806 F1130 D S L V G S H F E F R C R G T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 98.7 62 N.A. 92.5 39.6 N.A. N.A. 27.3 28.8 71.4 N.A. 21.5 N.A. N.A. N.A.
Protein Similarity: 100 98.2 99 68.2 N.A. 95.2 55.8 N.A. N.A. 43.4 44.7 81.4 N.A. 33.1 N.A. N.A. N.A.
P-Site Identity: 100 100 100 80 N.A. 80 0 N.A. N.A. 40 40 20 N.A. 33.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 86.6 6.6 N.A. N.A. 53.3 53.3 20 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 40 0 0 0 0 10 60 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 10 20 0 20 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 10 0 0 10 0 0 0 10 10 80 0 0 0 0 0 % F
% Gly: 0 0 0 0 20 10 20 0 10 0 0 0 20 80 0 % G
% His: 0 0 0 0 0 0 10 0 30 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 20 0 10 0 0 0 0 0 0 0 50 % K
% Leu: 0 60 90 0 0 0 0 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 30 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 10 10 0 0 0 0 0 0 10 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 30 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 10 0 0 0 10 0 0 0 0 10 0 % Q
% Arg: 80 0 0 40 50 0 0 0 10 0 10 10 80 0 0 % R
% Ser: 0 10 0 20 0 10 10 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 30 % T
% Val: 0 10 0 20 0 0 0 0 0 0 50 0 0 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 10 70 0 0 0 20 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _